phosphor mtor Search Results


93
Bioss p70 s6 kinase alpha polyclonal antibody
P70 S6 Kinase Alpha Polyclonal Antibody, supplied by Bioss, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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99
Cell Signaling Technology Inc mtor
Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity <t>of</t> <t>Akt,</t> p-Akt, AMPK, p-AMPK, <t>mTOR,</t> p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.
Mtor, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell Signaling Technology Inc phosphorylated p mtor
Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity <t>of</t> <t>Akt,</t> p-Akt, AMPK, p-AMPK, <t>mTOR,</t> p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.
Phosphorylated P Mtor, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 99 stars, based on 1 article reviews
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96
Santa Cruz Biotechnology phospho mtor
Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity <t>of</t> <t>Akt,</t> p-Akt, AMPK, p-AMPK, <t>mTOR,</t> p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.
Phospho Mtor, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/phospho mtor/product/Santa Cruz Biotechnology
Average 96 stars, based on 1 article reviews
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99
Cell Signaling Technology Inc phospho mtor ser2448 rabbit
Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity <t>of</t> <t>Akt,</t> p-Akt, AMPK, p-AMPK, <t>mTOR,</t> p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.
Phospho Mtor Ser2448 Rabbit, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ABclonal Biotechnology p-mtor-s2448 antibody
Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity <t>of</t> <t>Akt,</t> p-Akt, AMPK, p-AMPK, <t>mTOR,</t> p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.
P Mtor S2448 Antibody, supplied by ABclonal Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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96
Cell Signaling Technology Inc rabbit anti phospho mtor
Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity <t>of</t> <t>Akt,</t> p-Akt, AMPK, p-AMPK, <t>mTOR,</t> p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.
Rabbit Anti Phospho Mtor, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 96 stars, based on 1 article reviews
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86
Danaher Inc p mtor
Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity <t>of</t> <t>Akt,</t> p-Akt, AMPK, p-AMPK, <t>mTOR,</t> p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.
P Mtor, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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99
Cell Signaling Technology Inc anti phospho mtor
Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity <t>of</t> <t>Akt,</t> p-Akt, AMPK, p-AMPK, <t>mTOR,</t> p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.
Anti Phospho Mtor, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Huabio Inc mtor antibody
Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity <t>of</t> <t>Akt,</t> p-Akt, AMPK, p-AMPK, <t>mTOR,</t> p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.
Mtor Antibody, supplied by Huabio Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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94
Cell Signaling Technology Inc p mtor
Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity <t>of</t> <t>Akt,</t> p-Akt, AMPK, p-AMPK, <t>mTOR,</t> p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.
P Mtor, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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90
Cell Signaling Technology Inc phospho-mtor 5536 antibody
Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity <t>of</t> <t>Akt,</t> p-Akt, AMPK, p-AMPK, <t>mTOR,</t> p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.
Phospho Mtor 5536 Antibody, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity of Akt, p-Akt, AMPK, p-AMPK, mTOR, p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.

Journal: International journal of biological sciences

Article Title: Specific Pyruvate Kinase M2 Inhibitor, Compound 3K, Induces Autophagic Cell Death through Disruption of the Glycolysis Pathway in Ovarian Cancer Cells.

doi: 10.7150/ijbs.59855

Figure Lengend Snippet: Figure 7. Changes in the expression of various proteins in signaling pathways following PKM2 inhibition by compound 3K for 24 h. (A) The effect of PKM2 inhibition on signaling pathways in SK-OV-3 cells. Cells were treated with compound 3K, and western blot analysis was conducted to determine the expression levels of various signaling pathway proteins. (B) The band intensity of Akt, p-Akt, AMPK, p-AMPK, mTOR, p-mTOR, p70S6K, and p-p70S6K were calculated and expressed in the graph as a ratio of β-actin. The values represent the mean ± SD. *p < 0.05 and **p < 0.01.

Article Snippet: Primary antibodies against PKM2, PKM1, Cyclin B1, p-Cdc2, Cdc2, Bax, Bcl-2, caspase 3, Beclin-1, LC3B, Atg5, Atg7, p62, MMP-2, MMP-9, TIMP-2, p-AKT, AKT, p-AMPK, AMPK, p-mTOR, mTOR, p-p70S6K, p70S6K, GLUT1, LDHA, MCT4, and β-actin were all obtained from Cell Signaling (Beverly, MA, USA).

Techniques: Expressing, Protein-Protein interactions, Inhibition, Western Blot

Figure 10. Schematic diagram illustrating potential pathways associated with cell death in compound 3K-treated SK-OV-3 cells. Compound 3K-induced cell death is associated with the Akt/AMPK/mTOR signaling pathway. Compound 3K induces phosphorylation of AMPK at Thr172 and reduces the phosphorylation of Akt. These molecular changes cause the suppression of mTOR signaling, thereby regulating autophagy and apoptosis.

Journal: International journal of biological sciences

Article Title: Specific Pyruvate Kinase M2 Inhibitor, Compound 3K, Induces Autophagic Cell Death through Disruption of the Glycolysis Pathway in Ovarian Cancer Cells.

doi: 10.7150/ijbs.59855

Figure Lengend Snippet: Figure 10. Schematic diagram illustrating potential pathways associated with cell death in compound 3K-treated SK-OV-3 cells. Compound 3K-induced cell death is associated with the Akt/AMPK/mTOR signaling pathway. Compound 3K induces phosphorylation of AMPK at Thr172 and reduces the phosphorylation of Akt. These molecular changes cause the suppression of mTOR signaling, thereby regulating autophagy and apoptosis.

Article Snippet: Primary antibodies against PKM2, PKM1, Cyclin B1, p-Cdc2, Cdc2, Bax, Bcl-2, caspase 3, Beclin-1, LC3B, Atg5, Atg7, p62, MMP-2, MMP-9, TIMP-2, p-AKT, AKT, p-AMPK, AMPK, p-mTOR, mTOR, p-p70S6K, p70S6K, GLUT1, LDHA, MCT4, and β-actin were all obtained from Cell Signaling (Beverly, MA, USA).

Techniques: Phospho-proteomics